20+ Powerful Prayers For Deliverance and Breakthrough with Scriptures

Life is full of battles that are often invisible to the human eye. Many of the struggles we face are not only physical but deeply spiritual, tied to strongholds that can weigh us down, block our blessings, or hold us back from the life God has planned for us. Sometimes, despite working hard, nothing seems to move forward. At other times, we find ourselves bound by habits, fears, or unseen chains. In these moments, we need deliverance—God’s power to set us free from oppression, generational curses, and hidden hindrances. Alongside deliverance, we also need breakthrough—the hand of God opening doors that no man can shut, making a way where there seems to be no way, and bringing light into areas of our lives that have been stuck in darkness for too long.

Prayers for deliverance and breakthrough are not just ordinary words; they are cries from the heart that reach heaven and invite God’s mighty intervention. These prayers are rooted in faith, and in them, we remind ourselves that we serve a God who rescues, redeems, and restores. He is the same yesterday, today, and forever, and His promises never fail. Through prayer, we place every burden, every fear, and every obstacle into His hands, knowing that His power is greater than any force of darkness.

Below are heartfelt prayers for deliverance and breakthrough. Each prayer is anchored in Scripture, spoken with faith, and filled with trust in God’s unfailing love and authority. Whether you are facing financial struggles, spiritual attacks, health challenges, or emotional pain, may these prayers bring you closer to God, the One who fights for you, delivers you, and brings you into victory.

Powerful Prayers For Deliverance and Breakthrough with Scriptures

1. Breaking the Chains of Bondage

Every hidden chain that keeps us bound can be broken by the power of God.

“So if the Son sets you free, you will be free indeed.” – John 8:36

Lord Almighty, I come before You with a humble heart, asking for Your mercy and power to break every chain of bondage in my life. I surrender every hidden struggle, every weight that drags me down, and every power of darkness that tries to keep me bound. I declare by faith that no weapon formed against me shall prosper. Let the fire of Your Spirit consume every work of the enemy, and let freedom flow into every part of my life. Father, I refuse to remain a prisoner of fear, addiction, or oppression. I stand on Your promise that if the Son sets me free, I am free indeed. I believe today that chains are falling, doors are opening, and I am stepping into liberty through the blood of Jesus.

2. Deliverance from Fear

Fear cripples faith, but God’s perfect love casts out all fear.

“For God has not given us a spirit of fear, but of power and of love and of a sound mind.” – 2 Timothy 1:7

Gracious Father, I confess that fear has often controlled me, limiting my faith and stealing my peace. But today I declare that fear no longer has authority in my life. I stand on Your Word that You have not given me a spirit of fear, but of power, love, and a sound mind. Lord, let every anxious thought be silenced by the power of Your truth. Deliver me from fear of the unknown, fear of failure, fear of rejection, and fear of tomorrow. Let boldness rise within me, the boldness that comes from knowing that You are with me always. Fill me with Your Spirit so that I may walk courageously into every plan You have for me.

3. Financial Breakthrough

God desires to supply all our needs according to His riches in glory.

“And my God will meet all your needs according to the riches of his glory in Christ Jesus.” – Philippians 4:19

Father in Heaven, You are my Provider and Sustainer. You know the financial struggles that weigh on my heart, the debts that feel overwhelming, and the doors that seem shut. I ask for Your divine intervention and a financial breakthrough in my life. Open doors of provision, Lord, and bless the work of my hands. Let opportunities flow that will lift me out of lack and into abundance. Teach me wisdom to manage resources well and to use every blessing for Your glory. I trust You to meet all my needs according to Your riches in Christ Jesus. Lord, release me from every spirit of financial stagnation, and let breakthrough flow into every area of my finances.

4. Healing from Emotional Wounds

Deliverance is not only from external enemies but also from the pain we carry inside.

“He heals the brokenhearted and binds up their wounds.” – Psalm 147:3

Heavenly Father, I come to You with a heart that has been wounded by disappointment, betrayal, and pain. Lord, I ask for Your healing touch over my emotions. Where there has been hurt, bring comfort. Where there has been bitterness, bring forgiveness. Where there has been sadness, bring joy. Father, deliver me from the spirit of heaviness and restore to me the joy of salvation. Bind up every wound within me and fill me with peace that surpasses all understanding. Lord, I lay my brokenness before You, trusting that You will make me whole again.

5. Deliverance from Generational Curses

Some struggles follow family lines, but the blood of Jesus has the final say.

“Christ redeemed us from the curse of the law by becoming a curse for us.” – Galatians 3:13

Mighty Deliverer, I bring before You every generational pattern of failure, sickness, or oppression that has followed my family line. I declare by the blood of Jesus that I am redeemed from every curse. No power of the past has authority over my present or future. Lord, break every negative cycle that has held me or my family captive. Let every curse be replaced with blessing, and every darkness with light. I stand in the authority of Christ, declaring freedom for myself and my household. From this day forward, I walk in victory and generational blessings in Jesus’ name.

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6. Prayer for Deliverance from Spiritual Attacks

The enemy seeks to attack us through many forms, but the Lord is our shield and protector.

“The Lord is faithful, and he will strengthen you and protect you from the evil one.” – 2 Thessalonians 3:3

Almighty God, I come under the shadow of Your wings, seeking protection and deliverance from every spiritual attack set against me. Lord, You see the arrows of the enemy—arrows of discouragement, confusion, sickness, and setbacks—that have been fired into my life. Today, I lift up my shield of faith, declaring that no weapon formed against me shall prosper. Father, destroy every plan of the enemy concerning my destiny, and silence every voice that speaks against my progress. I pray for spiritual covering over my home, my family, my work, and my mind. Strengthen me in the inner man to stand firm in faith. Let the blood of Jesus be a wall of fire around me, and let Your angels encamp around me, fighting battles I cannot see. I trust You, Lord, for complete deliverance from every spiritual attack, and I walk in the assurance that victory is already mine.

7. Prayer for Breakthrough in Career and Work

God grants favor and opens doors that no man can shut in our careers and daily labor.

“You will eat the fruit of your labor; blessings and prosperity will be yours.” – Psalm 128:2

Father, I thank You for the work of my hands and the opportunities You have given me to grow. Yet Lord, You know the barriers and hindrances I face in my career and work. Today, I ask for divine breakthrough that will lift me to new heights. Let every closed door be opened, and every denied opportunity be restored. Father, bring favor before those who make decisions, and let my work shine as a testimony of Your grace. Deliver me from the spirit of stagnation, rejection, and limitation. Let creativity, wisdom, and excellence flow through me, setting me apart in my workplace. Lord, guide me into opportunities that will not only bless me but also enable me to be a blessing to others. May my career be a channel of breakthrough and prosperity, bringing honor to Your name.

8. Prayer for Deliverance from Sinful Habits

Sin holds us captive, but God gives us the power to overcome through His Spirit.

“For sin shall no longer be your master, because you are not under the law, but under grace.” – Romans 6:14

Merciful Father, I come before You, acknowledging my weakness and the sinful habits that have held me captive. Lord, I know that sin is destructive and separates me from Your perfect will, but I believe in the power of Your grace to set me free. Deliver me from every hidden sin that entangles me, whether in thought, word, or action. Let the blood of Jesus cleanse me from guilt and shame. Fill me with the strength of the Holy Spirit, empowering me to resist temptation and walk in holiness. Lord, replace my desires for sinful pleasures with a hunger for righteousness. Help me to guard my heart, watch my steps, and depend fully on You. I declare today that sin shall not have dominion over me, because I live under the covering of grace.

9. Prayer for Deliverance from Depression

The Lord is close to the brokenhearted and rescues those crushed in spirit.

“The Lord is close to the brokenhearted and saves those who are crushed in spirit.” – Psalm 34:18

Compassionate God, You see the heaviness in my heart and the weariness that tries to overwhelm my soul. Depression has sought to steal my joy and silence my praise, but I turn to You for deliverance. Lord, let Your light shine into every dark corner of my mind and fill me with renewed hope. Deliver me from the lies that whisper defeat and despair. Replace sorrow with peace, and heaviness with the oil of gladness. Surround me with Your love and remind me of my worth in Christ. Father, I refuse to let depression define me, for You have called me more than a conqueror. Lord, breathe life into my spirit again, and let me rise with strength, joy, and a testimony that glorifies Your name.

10. Prayer for Breakthrough in Family Relationships

God desires harmony and unity in families, bringing peace where there has been strife.

“How good and pleasant it is when God’s people live together in unity!” – Psalm 133:1

Heavenly Father, I lift my family before You, asking for deliverance from strife, misunderstanding, and division. Lord, heal every broken relationship within my family and restore peace where there has been conflict. Deliver us from bitterness, unforgiveness, and pride that hinder love and unity. I pray for breakthrough in communication, that every word spoken may bring healing instead of hurt. Father, let Your Spirit of peace dwell in our home. Help us to forgive as Christ forgave us, and to bear one another’s burdens in love. Lord, strengthen the bonds of love, and let harmony and joy overflow within my family. May our unity be a testimony of Your grace, and may our home be a dwelling place of Your presence.

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11. Prayer for Deliverance from Doubt and Unbelief

Faith is the key to unlocking God’s promises, but doubt keeps doors closed.

“Immediately the boy’s father exclaimed, ‘I do believe; help me overcome my unbelief!’” – Mark 9:24

Lord of all creation, I confess that there are moments when doubt and unbelief cloud my heart. Sometimes, I struggle to trust Your promises when challenges surround me. Today, I pray for deliverance from the spirit of doubt and unbelief. Strengthen my faith, Lord, and help me to stand on Your Word even when circumstances seem impossible. Teach me to trust that nothing is too hard for You, and that every delay is part of Your divine plan. Father, I surrender my doubts to You, and I ask that You fill me with unwavering confidence in Your power and love. Help me to walk by faith, not by sight, and to believe that my breakthrough is on the way.

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12. Prayer for Breakthrough in Health

God is our healer, able to restore every part of our body and mind.

“But I will restore you to health and heal your wounds, declares the Lord.” – Jeremiah 30:17

Faithful Healer, I come before You, lifting up every weakness, sickness, and affliction in my body. Lord, You are the Great Physician, and nothing is impossible for You. I ask for complete healing and breakthrough in my health. Deliver me from every sickness that drains my strength, every diagnosis that causes fear, and every condition that hinders my daily life. Let the blood of Jesus flow through my body, bringing renewal and restoration. Father, I pray that every organ, every cell, and every system in my body will align with Your Word. Grant me strength where there has been weakness, peace where there has been worry, and life where there has been decay. I believe, Lord, that by Your stripes I am healed.

13. Prayer for Deliverance from Stagnation

Stagnation keeps us stuck, but God’s power brings forward movement and progress.

“The Lord will make you the head, not the tail. If you pay attention to the commands of the Lord your God, you will always be at the top, never at the bottom.” – Deuteronomy 28:13

Mighty God, I present before You every area of my life that has been stagnant—whether in my career, relationships, spiritual growth, or finances. Lord, deliver me from cycles of delay and barriers that keep me from moving forward. Break every chain of limitation and open doors that have been closed for too long. Father, release fresh anointing for progress and advancement. Guide my steps to opportunities that will propel me into new levels of blessing. Lord, I reject backwardness and declare that I will not remain stuck. By Your power, I will move forward, upward, and onward into the destiny You have prepared for me.

14. Prayer for Breakthrough in Marriage

A marriage blessed by God can withstand storms and flourish in love.

“Therefore what God has joined together, let no one separate.” – Mark 10:9

Lord, I thank You for the gift of marriage and the covenant You have ordained. I bring my marriage before You, asking for breakthrough in areas where we have struggled. Deliver us from miscommunication, selfishness, and any schemes of the enemy to bring division. Father, pour out Your love afresh into our hearts so that we may love one another as Christ loves the church. Let forgiveness replace bitterness, and let unity overcome division. Teach us to pray together, serve together, and grow together. Lord, restore joy, intimacy, and peace in our marriage, and let it shine as a reflection of Your love to the world.

15. Prayer for Deliverance from Addiction

Addictions can enslave us, but God’s power breaks every yoke.

“It is for freedom that Christ has set us free. Stand firm, then, and do not let yourselves be burdened again by a yoke of slavery.” – Galatians 5:1

Lord of freedom, I bring before You every addiction that has entangled me or my loved ones. Whether it is addiction to substances, habits, or destructive behaviors, I ask for Your mighty deliverance. Break every chain of bondage and remove every craving that does not glorify You. Fill the emptiness in my heart with Your Spirit and peace. Replace every destructive desire with a hunger for Your presence and Word. Lord, give me strength to stand firm and resist every temptation. Surround me with godly support and accountability, and remind me daily that I am free through Christ. Let my life be a testimony of Your power to break addictions and restore wholeness.

16. Prayer for Breakthrough in Spiritual Growth

God desires us to grow deeper in Him, moving from glory to glory.

“But grow in the grace and knowledge of our Lord and Savior Jesus Christ.” – 2 Peter 3:18

Father, I hunger for more of You. I long to grow deeper in my faith and closer in my walk with You. Deliver me from every distraction that steals my time with You and every hindrance that keeps me from maturing in Christ. Lord, give me a fresh hunger for prayer, for Your Word, and for fellowship with You. Break through the walls of spiritual dryness and let living water flow into my soul. Fill me with the Spirit of wisdom and revelation so that I may know You better each day. Lord, let my faith be strengthened, my love deepened, and my testimony multiplied as I grow in Your grace and truth.

17. Prayer for Deliverance from Poverty

God’s plan for us is abundance, not poverty and lack.

“The Lord will open the heavens, the storehouse of his bounty, to send rain on your land in season and to bless all the work of your hands.” – Deuteronomy 28:12

Jehovah Jireh, my Provider, I lay before You every financial struggle and burden that weighs me down. Lord, deliver me from the cycle of lack and insufficiency. Break every curse of poverty and open the windows of heaven to pour out blessings. Teach me diligence, discipline, and stewardship in all that You entrust to me. Father, bless the work of my hands and establish the labor of my efforts. Let financial breakthrough flow into my life, not only for my needs but also so I may bless others. I reject poverty and embrace abundance, for You are a God who supplies more than enough.

18. Prayer for Breakthrough in Ministry and Calling

God equips and empowers us for the purpose He has set before us.

“Now to each one the manifestation of the Spirit is given for the common good.” – 1 Corinthians 12:7

Lord, I thank You for the gifts and calling You have placed upon my life. Father, I ask for breakthrough in fulfilling my divine assignment. Deliver me from fear, doubt, and anything that holds me back from serving You wholeheartedly. Open doors of ministry and influence so that I may impact lives for Your kingdom. Fill me with the power of the Holy Spirit and grant me wisdom to walk in obedience. Lord, let every gift You have deposited in me come alive for Your glory. May my life be a channel of blessing, and may Your name be exalted through every work I do in Your service.

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19. Prayer for Deliverance from Negative Thoughts

Our minds are battlegrounds, but God’s Word renews and transforms us.

“Do not conform to the pattern of this world, but be transformed by the renewing of your mind.” – Romans 12:2

Father, I bring my mind before You today. Deliver me from negative thoughts, lies of the enemy, and self-condemning voices. Lord, I reject every spirit of confusion, hopelessness, and defeat. Let my thoughts align with Your Word and Your promises. Fill my mind with peace, joy, and confidence in Christ. Teach me to meditate on whatever is true, noble, right, pure, lovely, and admirable. Lord, transform me by the renewing of my mind, so that I may discern Your will and walk in freedom. From this day forward, my mind is guarded by the peace of Christ, and my thoughts are established in truth.

20. Prayer for Breakthrough into New Beginnings

God makes all things new and gives us fresh seasons of grace.

“Forget the former things; do not dwell on the past. See, I am doing a new thing!” – Isaiah 43:18-19

Father of new beginnings, I thank You that my past does not define me. Lord, I release every disappointment, failure, and pain of yesterday into Your hands. Deliver me from dwelling on the past and open my eyes to the new things You are doing in my life. Lord, I pray for breakthrough into fresh opportunities, open doors, and divine connections. Let new strength, new joy, and new hope rise within me. Father, order my steps into a new season of abundance and victory. I trust that You are making a way in the wilderness and streams in the desert. Lord, let this be the dawn of new beginnings in every area of my life.

Conclusion

Deliverance and breakthrough are two powerful promises that God has made available to His children through the sacrifice of Jesus Christ on the cross. When we call upon Him in faith, He not only rescues us from the grip of sin, bondage, and fear, but He also ushers us into a life of victory, abundance, and divine favor. These Prayers for Deliverance and Breakthrough are more than just words; they are declarations of faith, rooted in God’s Word, that have the power to shift situations and open doors that seemed permanently shut.

Life brings many battles—spiritual attacks, health challenges, financial struggles, family conflicts, and inner battles with doubt or depression. At times, it may feel as though the chains are too strong and the mountains too high to move. But as we have prayed through these powerful prayers, we are reminded that there is no chain too heavy for God to break and no mountain too high for Him to move. His Word declares, “The Lord is faithful, and he will strengthen you and protect you from the evil one” (2 Thessalonians 3:3). That promise stands sure for every believer who places their trust in Him.

One of the key truths to remember is that deliverance is not just about being set free once, but about walking daily in the freedom Christ has given us. Breakthrough is not only about a single answered prayer, but about stepping into a new season where God’s power and favor continually open doors before us. It is a process of trusting God, even when the answers are delayed, and continuing to pray with persistence and faith until His promises manifest in full.

Each prayer—whether for deliverance from spiritual attacks, breakthrough in career, healing from depression, restoration in family relationships, or freedom from poverty—points us back to the same truth: God is our Deliverer, and He delights in bringing His children into freedom. When we pray, we are not merely speaking into the air; we are calling upon the Almighty God who hears, who cares, and who acts on our behalf.

As you meditate on these prayers, let them not just be one-time recitations. Instead, use them as daily spiritual weapons, as reminders that God’s promises are alive and active in your life. Speak them over your situation, declare them over your family, and believe them for your future. Prayer is not about how eloquent our words are, but about the faith we carry in our hearts.

Remember also that breakthrough often requires persistence. Just as Daniel prayed for 21 days before the answer was released, and as the walls of Jericho fell after seven days of obedience, sometimes our deliverance and breakthrough come through consistent faithfulness in prayer. Do not give up when the answers seem delayed. Continue to trust, continue to believe, and continue to pray.

In addition, it is important to combine prayer with obedience and faith-filled action. When we ask God for deliverance, we must also walk away from habits, places, or associations that keep us bound. When we pray for financial breakthrough, we must be diligent, disciplined, and faithful stewards. When we ask for healing, we must also take steps of faith to live in health. God does His part, but He also calls us to align our lives with His will so that His blessings can flow unhindered.

Beloved, as you walk away from this collection of prayers, know that you are not walking away empty-handed. You are walking away empowered, strengthened, and surrounded by the presence of God. His Spirit is your guide, His Word is your sword, and His promises are your inheritance. Deliverance is yours. Breakthrough is yours. Freedom is yours.

Stand tall, declare your victory, and walk boldly into the new season God has prepared for you. The same God who parted the Red Sea, who broke Paul and Silas out of prison, and who raised Lazarus from the dead, is the same God working in your life today. He is faithful to deliver, and He is faithful to bring breakthrough.

Now, lift your head high and believe with all your heart: your season of breakthrough has come, and your deliverance is already secured in Christ Jesus.

Amen. 

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